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See also: Quinolones Quintessential Quintessence Quinoa Quinceanera Quin Quints Quintel Quintessa Quincy Quinces Quine Quink Quinn Quinny Quinsy Quinta

1. Quinolones are a type of antibiotic. Antibiotics kill or inhibit the growth of bacteria

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2. In addition, another class of antibiotic, called fluoroQuinolones, were derived from Quinolones by modifying their structure with fluorine.

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3. Quinolones are bactericidal and exhibit concentration-dependent killing

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4. Quinolone activity: Early Quinolones, such as nalidixic acid, had poor systemic distribution and limited activity and were used

Quinolone, Quinolones

5. Quinolones are antimicrobial agents that trap two essential enzymes, gyrase and topoisomerase IV, on DNA as reversible drug–enzyme–DNA complexes. The DNA strands in the complexes are broken with their ends held by protein

Quinolones

6. Marbofloxacin (Also called Zeniquin and is one of the FluoroQuinolones Used for Dogs and Cats) Mefloquine – An Antimalarial drug that can lead …

7. The quinolone class is one of the most important classes of antibiotics identified in the past 50 years. The discovery of fluoroQuinolones in the 1980s constituted a breakthrough due to their excellent broad-spectrum activity that includes Gram-negative pathogens.

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8. Most Quinolones have excellent oral bioavailability, with serum drug concentrations equivalent to intravenous administration

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9. Quinolones are a type of antibiotic that has much more serious side effects than was known when they were first approved by the FDA. The most popular Quinolones are fluoroQuinolones, which include ciprofloxacin (Cipro), lomefloxacin (Maxaquin), norfloxacin (Noroxin), ofloxacin (Floxin), moxifloxacin (Avelox) and levofloxacin (Levaquin).

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10. Quinolones A class of broad-spectrum antibacterial drugs of which the main ophthalmic agents are ciprofloxacin and ofloxacin

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11. FluoroQuinolones are generally very safe antibiotics which do not cause serious or life-threatening adverse reactions

12. The safety of Quinolones--a meta-analysis of pregnancy outcomes

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13. Although attempts have been made to standardize skin testing, the diagnosis of immediate hypersensitivity reactions to Quinolones is mainly based on drug provocation

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14. The MHRA and CHM have released important safety information regarding the use of systemic and inhaled fluoroQuinolones

15. For restrictions and precautions, see Important safety information for all Quinolones: ciprofloxacin, delafloxacin, levofloxacin, moxifloxacin, and ofloxacin.

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16. Quinolones typically have few side effects, most commonly including nausea, headache, dizziness, and confusion

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17. Quinolones are a group of synthetic broad-spectrum antimicrobials, whose mechanism of action is the inhibition of DNA gyrase and topoisomerase IV, with the consequent DNA breakdown and cell death due to genotoxic damage

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18. Three mechanisms have been determined by which bacteria can be resistant to Quinolones: (1) Chromosomal mutations in coding

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19. Quinolones and fluoroQuinolones consists of drugs which act as chemotherapeutic agents against bacteria consisting of drugs which generally contain the term “oxacin” in the end

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20. FluoroQuinolones and Quinolones cause severe side effects in rare cases and are therefore not used for regular treatment of bacterial infections.

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21. There is some evidence that antibiotics, especially the Quinolones, e.g

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22. Quinolones are known to select for quinolone-resistant Salmonella and E

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23. At the same time, Quinolones are one of few available therapies for serious Salmonella and E

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24. Quinolones cause arthropathy in the weight-bearing joints of immature animals and are therefore generally not recommended in children and growing adolescents

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25. Quinolones are commonlyused to treat a widevariety of infectious diseases,such as community-acquired pneumoniaand urinary tract infections

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26. SomeQuinolones are also given as prophylaxisfor spontaneous bacterial peritonitis.These popular antimicrobial agents areassociated with several clinically significantdrug interactions, which can beclassified into 2 major categories1-3:

27. Learn Quinolones with free interactive flashcards

Quinolones

28. Choose from 500 different sets of Quinolones flashcards on Quizlet.

Quinolones, Quizlet

29. Absorption of the Quinolones is known to be reduced in the presence of divalent or trivalent metal cations, such as Mg 2+, Ca 2+, Al 3+, or Fe 3+, due to chelation of the cation to the quinolone carbonyl and carboxylate groups; the bioavailability of the Quinolones is, therefore, limited by co-administration with metal cation-rich products

Quinolones, Quinolone

30. Quinolones are used in a large variety of in-hospital and community infections, as the treatment of choice or as alternative therapy

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31. Learn Quinolones antibiotics with free interactive flashcards

Quinolones

32. Choose from 114 different sets of Quinolones antibiotics flashcards on Quizlet.

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33. Our objective was to evaluate the association between the administration of Quinolones and seizures for three groups of children: those with epilepsy; those with other CNS …

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34. Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria

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35. New Quinolones are continually being developed as bacterial species develop resistance to existing Quinolones.

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36. Quinolones represent an important option for treatment of P

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37. Regarding to the research of Quinolones and sulfonamides, among 99 samples were analyzed, being four of them positive for quinolone group, and six samples showed positive results for sulfonamides residues (Table 1).

Quinolones, Quinolone

38. The third-generation Quinolones currently include levofloxacin, gatifloxacin, moxifloxacin and sparfloxacin

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39. All Quinolones have activity against oral anaerobes, but only trovafloxacin provides coverage against Bacteroides fragilis, the primary anaerobe of the abdomen/pelvis

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40. In addition, Quinolones are very active against atypical pulmonary pathogens, e.g., Legionella, but trovafloxacin is …

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41. Other articles where Quinolone is discussed: antibiotic: The first antibiotics: …class of antibiotics known as Quinolones

Quinolone, Quinolones

42. Quinolones interrupt the replication of DNA—a crucial step in bacterial reproduction—and have proven useful in treating urinary tract infections, infectious diarrhea, and various other infections involving elements such as bones and white blood cells.

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43. Search results for Quinolones at Sigma-Aldrich

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44. Quinolones have a broad antibacterial spectrum and strong antibacterial effect

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45. Coupled with the special mechanism of action of Quinolones, it can be used with other antibiotics without worrying about the drug resistance

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46. Quinolones Generic Trade Name First generation Nalidixic acid* NegGram* (Sanofi-Aventis, Bridgewater, NJ) Second generation Ciprofloxacin Cipro (Bayer Pharmaceuticals, Germany) Norfloxacin Noroxin (Merck, Whitehouse Station, NJ) Ofloxacin Floxin (Ortho-McNeil, Titusville, NJ)

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47. The Quinolones are carboxylic acids and contain a quinolone ring

Quinolones, Quinolone

48. Systemically effective, broad spectrum Quinolones possess a fluoro group on the main ring

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49. The fluoroQuinolones also contain protonatable nitrogens and, therefore, can exist as zwitterions

50. Quinolones can enter cells easily via porins and, therefore, are often used to treat intracellular pathogens such as Legionella pneumophila and Mycoplasma pneumoniae

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51. Quinolones Market: Regional Analysis

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52. The global Quinolones market can be segmented into different regions such as North America, Asia Pacific (APAC), Europe, Latin America, Middle East & Africa and Rest of World (RoW)

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53. Where North America and the Asia Pacific holds a major market share in the Quinolones global market in the current time.

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Dictionary

QUINOLONES [ˈkwinəlōn, ˌkwinlˈōn]

NOUN

  • any of a class of antibiotics derived from quinoline and used chiefly against Gram-negative organisms.

Frequently Asked Questions

What does quinolones mean?

Medical Definition of quinolone. : any of a class of synthetic antibacterial drugs that are derivatives of hydroxylated quinolines and inhibit the replication of bacterial DNA especially : fluoroquinolone. More from Merriam-Webster on quinolone.

Is quinolone a group of antibiotic?

Quinolone is a group of antibiotic which acts by inhibiting enzymatic activities of two members of the topoisomerase class of enzymes, DNA gyrase and topoisomerase IV. 8 million inpatients who received an injectable quinolone in 2011.

What is a quinolone drug?

Medical Definition of quinolone. : any of a class of synthetic antibacterial drugs that are derivatives of hydroxylated quinolines and inhibit the replication of bacterial DNA especially : fluoroquinolone.

Are quinolones and fluoroquinolones safe?

Are quinolones and fluoroquinolones safe? Quinolones and fluoroquinolones should be avoided in children under the age of 18 years unless they have a serious infection that cannot be treated with any other antibiotic.

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