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See also: Mesalamine Mechanism Mecate Mecatronica Mecanografia Mechanic Mechanize Mechanical Mechanoreceptor Mechanics Mercantilism Mercantile Mercator Me Mechas Mechada Mechante Mechanist Mechanoid

1. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure). Because of its many side effects, Mecamylamine is not commonly used

Mecamylamine, Moderate, Many

2. Mecamylamine is also used to treat malignant hypertension (extremely high blood pressure that comes on suddenly)

Mecamylamine, Malignant

3. Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine

Mecamylamine

4. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension

Mecamylamine, Management, Moderately, Malignant

5. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals.

Mecamylamine

6. Mecamylamine is used to treat moderately severe to severe high blood pressure. It can also be used in sudden high blood pressure emergencies (malignant …

Mecamylamine, Moderately, Malignant

7. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure). Because of its many side effects, Mecamylamine is not commonly used

Mecamylamine, Moderate, Many

8. Mecamylamine is also used to treat malignant hypertension (extremely high blood pressure that comes on suddenly)

Mecamylamine, Malignant

9. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure). Because of its many side effects, Mecamylamine is not commonly used

Mecamylamine, Moderate, Many

10. Mecamylamine is also used to treat malignant hypertension (extremely high blood pressure that comes on suddenly)

Mecamylamine, Malignant

11. Mecamylamine, a noncompetitive and nonspecific nAChR antagonist, was seminal in establishing the involvement of nAChRs in relation to effects of alcohol in the mesocorticolimbic pathway.

Mecamylamine, Mesocorticolimbic

12. Mecamylamine hydrochloride has been used as an additive in extracellular saline during current-clamp recordings to reduce synaptic input. I It has also been used as a non-selective nicotinic acetyl choline receptor blocker in aortic body neurons and in MLO-Y4 cells.

Mecamylamine, Mlo

13. Inversine (Mecamylamine)." Merc & Co Inc, West Point, PA.

Mecamylamine, Merc

14. Mecamylamine is a nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier.Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Mecamylamine, Most, More

15. Mecamylamine is also sometimes used as an anti-addictive drug to help people stop smoking tobacco, and is now

Mecamylamine

16. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure)

Mecamylamine, Moderate

17. Because of its many side effects, Mecamylamine is not commonly used

Many, Mecamylamine

18. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure)

Mecamylamine, Moderate

19. Because of its many side effects, Mecamylamine is not commonly used

Many, Mecamylamine

20. Mecamylamine is also used to treat malignant hypertension (extremely high blood pressure that comes on suddenly)

Mecamylamine, Malignant

21. Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine

Mecamylamine

22. Mecamylamine is indicated for the management of moderately severe to severe essential hypertension and in uncomplicated cases of malignant hypertension

Mecamylamine, Management, Moderately, Malignant

23. Mecamylamine reduces blood pressure in both normotensive and hypertensive individuals.

Mecamylamine

24. DESCRIPTION INVERSINE® (Mecamylamine HCl) is a potent, oral antihypertension agent and ganglion blocker, and is a secondary amine

Mecamylamine

25. Supplementation of the drinking water of mice with nicotine increased the size of CNV lesions at Bruch membrane rupture sites, an effect that was blocked by subcutaneous administration of Mecamylamine (50 mg/kg/d) by an osmotic pump.

Mice, Membrane, Mecamylamine, Mg

26. Mecamylamine is a autonomic ganglionic blocker that is FDA approved for the {{{indicationType}}} of moderately severe to severe essential hypertension and uncomplicated cases of malignant hypertension

Mecamylamine, Moderately, Malignant

27. Mecamylamine, a nicotinic receptor channel antagonist, affects amylase secretion by isolated pancreatic acinar cells

Mecamylamine

28. (-)-Mecamylamine Hydrochloride C11H22ClN CID 12358973 - structure, chemical names, physical and chemical properties, classification, patents, literature

Mecamylamine

29. Definition of Mecamylamine : a drug that is used orally in the form of its hydrochloride C11H21N·HCl as a ganglionic blocking agent to effect a rapid lowering of severely elevated blood pressure Examples of Mecamylamine in a Sentence

Mecamylamine

30. Mecamylamine definition: a ganglion-blocking drug administered orally to lower high blood pressure

Mecamylamine

31. Mecamylamine hydrochloride is a non-selective, non-competitive nAChR antagonist, has oral activity, and has certain therapeutic effects on various neuropsychiatric diseases

Mecamylamine

32. Mecamylamine (Inversine), the first orally available antihypertensive agent launched in the 1950s, is rarely used today for hypertension because of its widespread ganglionic side effects at antihypertensive doses (25 - 90 mg/day).

Mecamylamine, Mg

33. Mecamylamine HCl A nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier

Mecamylamine

34. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Mecamylamine, Most, More

35. Mecamylamine definition at Dictionary.com, a free online dictionary with pronunciation, synonyms and translation

Mecamylamine

36. Modeling study of Mecamylamine block of muscle type acetylcholine receptors

Modeling, Mecamylamine, Muscle

37. Eur.Biophys.J., 2007;37:393 The nicotinic antagonist Mecamylamine has antidepressant-like effects in wild-type but not β2- or α7-nicotinic acetylcholine receptor subunit knockout mice.

Mecamylamine, Mice

38. Mecamylamine (INN, BAN; or Mecamylamine hydrochloride (); brand names Inversine, Vecamyl [1]) is a non-selective, non-competitive antagonist of the nicotinic acetylcholine receptors (nAChRs) that was introduced in the 1950s as an antihypertensive drug

Mecamylamine

39. Mecamylamine is an anti hypersensitive drug used for hypertension and of malignant hypertension

Mecamylamine, Malignant

40. Mecamylamine, a secondary amine, readily penetrates into the brain and thus may produce central nervous system effects.Tremor, choreiform movements, mental aberrations, and convulsions may occur rarely

Mecamylamine, May, Movements, Mental

41. These have occurred most often when large doses of Mecamylamine HCl were used, especially in patients with cerebral or renal insufficiency.

Most, Mecamylamine

42. Mecamylamine (Inversine®), the first orally available antihypertensive agent, is now rarely used

Mecamylamine

43. Although celebrated in the 1950s, Mecamylamine fell …

Mecamylamine

44. "Mecamylamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Mecamylamine, Medicine, Mesh, Medical

45. Synonym: Mecamylamine Hydrochloride - CAS 826-39-1 - Calbiochem Empirical Formula (Hill Notation): C 11 H 21 N · xHCl Molecular Weight: 167.29 (free base basis)

Mecamylamine, Molecular

46. Mecamylamine hydrochloride is an orally active, nonselective, noncompetitive nAChR antagonist that can treat various neuropsychiatric disorders

Mecamylamine

47. Mecamylamine hydrochloride is originally used as a ganglionic blocker in treating hypertension

Mecamylamine

48. Mecamylamine hydrochloride can easily crosses the blood-brain barrier

Mecamylamine

49. Mecamylamine, a secondary amine, readily penetrates the brain and thus may produce central nervous system effects

Mecamylamine, May

50. These have occurred most often when large doses of Mecamylamine HCl were used, especially in patients with cerebral or renal insufficiency.

Most, Mecamylamine

51. Mecamylamine was the first orally available antihypertensive agent introduced in the 1950s

Mecamylamine

52. Mecamylamine (Vecamyl) Policy # 00528 Original Effective Date: 01/01/2017 Current Effective Date: 01/01/2017 ©2017 Blue Cross and Blue Shield of Louisiana An independent licensee of the Blue Cross and Blue Shield Association No part of this publication may be reproduced, stored in a retrieval system, or transmitted, in any form or by any means,

Mecamylamine, May, Means

53. Mecamylamine A nonselective and noncompetitive ganglion-blocker once used to treat severe malignant hypertension

Mecamylamine, Malignant

54. Mecamylamine binds ± 1/2 of nicotinic acetylcholine receptors; it may be effective in smoking cessation and can be used with nicotine replacement therapy (e.g., gum or patches).

Mecamylamine, May

55. Mecamylamine (Inversine), the first orally available antihypertensive agent launched in the 1950s, is rarely used today for hypertension because of its widespread ganglionic side effects at antihypertensive doses (25 - 90 mg/day)

Mecamylamine, Mg

56. However, more recent clinical studies suggest that Mecamylamine is effective at much lower doses for blocking the

More, Mecamylamine, Much

57. Mecamylamine se usa para tratar la hipertensión (presión arterial alta) moderada a severa

Mecamylamine, Moderada

58. Debido a sus muchos efectos secundarios, Mecamylamine no se usa con frecuencia

Muchos, Mecamylamine

59. Mecamylamine también se usa para tratar la hipertensión maligna (presión arterial extremadamente alta que aparece repentinamente)

Mecamylamine, Maligna

60. Mecamylamine is used to treat moderate to severe hypertension (high blood pressure).Because of its many side effects, Mecamylamine is not commonly used

Mecamylamine, Moderate, Many

61. Mecamylamine is also used to treat malignant hypertension (extremely high blood pressure that comes on suddenly)

Mecamylamine, Malignant

62. Mecamylamine may also be used for purposes not listed …

Mecamylamine, May

63. Medscape - Indication-specific dosing for Mecamylamine, frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information.

Medscape, Mecamylamine

64. "Mecamylamine" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings).Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

Mecamylamine, Medicine, Mesh, Medical

65. Mecamylamine HCl is almost completely absorbed from the gastrointestinal tract, resulting in consistent lowering of blood pressure in most patients with hypertensive cardiovascular disease

Mecamylamine, Most

66. Mecamylamine HCl is excreted slowly in the urine in the unchanged form

Mecamylamine

67. This is a preliminary study of the antihypertensive drug Mecamylamine, used in the specific circumstance of hypertension caused by autonomic dysreflexia (AD), a condition that affects people with spinal cord injury (SCI).

Mecamylamine

68. Vecamyl (Mecamylamine) is a very potent blood pressure-lowering medication for moderate, severe, and emergency high blood pressure

Mecamylamine, Medication, Moderate

69. Shytle et al., 2002, Mecamylamine (Inversine): an old antihypertensive with new research directions., J Hum Hypertens Eaton JB et al., 2003, Characterization of human alpha 4 beta 2-nicotinic acetylcholine receptors stably and heterologously expressed in native nicotinic receptor-null SH-EP1 human epithelial cells., Mol Pharmacol

Mecamylamine, Mol

70. Mecamylamine synonyms, Mecamylamine pronunciation, Mecamylamine translation, English dictionary definition of Mecamylamine

Mecamylamine

71. Mecamylamine has also been found to abolish the plasma corticosterone response to auditory stress in rats (Sithichoke and Marotta, 1978)

Mecamylamine, Marotta

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MECAMYLAMINE

Frequently Asked Questions

What does mecamylamine mean?

Definition of mecamylamine : a drug that is used orally in the form of its hydrochloride C 11H 21N·HCl as a ganglionic blocking agent to effect a rapid lowering of severely elevated blood pressure

Is mecamylamine a ganglionic blocker?

Mecamylamine has been used as an orally-active ganglionic blocker in treating autonomic dysreflexia and hypertension, but, like most ganglionic blockers, it is more often used now as a research tool.

Is mecamylamine a secondary amine?

Mecamylamine is a potent, oral antihypertensive agent and ganglion blocker, and is a secondary amine.

What is the mechanism of action of mecamylamine?

8.5 Mechanism of Action. Mecamylamine is a ganglionic blocker which prevents stimulation of postsynaptic receptors by acetylcholine released from presynaptic nerve endings. The hypotensive effect of Mecamylamine is attributed to reduction in sympathetic tone, vasodilation, and reduced cardiac output, and is primarily postural.

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