1. Cytopenias are a common occurrence following CAR T-cell infusion. Grades 3–4 anemias, thrombocytopenia, leukopenia, neutropenia, and lymphopenia are frequently reported
Cytopenias, Common, Car, Cell
2. There is often difficulty in determining the etiology of Cytopenias occurring after CAR T-cell infusions.
Cytopenias, Car, Cell
3. Cytopenias associated with alemtuzumab are often transient, although erythrocyte and platelet transfusions may be required (181 R)
4. Grade 3–4 Cytopenias have been observed in patients with mycosis fungoides receiving intravenous alemtuzumab 30 …
5. There are various immune Cytopenias associated with systemic lupus erythematosus (SLE)
6. Studies characterizing the CVID phenotype associated with autoimmune Cytopenias have mostly been limited to large referral centers.
Characterizing, Cvid, Cytopenias, Centers
7. This topic review discusses an approach to evaluating and managing Cytopenias (anemia, thrombocytopenia, neutropenia, pancytopenia) in people with HIV
8. As with the anemias, the other Cytopenias can be thought about in two broad categories to explain their causes: 1) decreased cellular production, or 2) increased cellular destruction.
Cytopenias, Can, Categories, Causes, Cellular
9. There is great variation in Cytopenias in cirrhotic patients with same severity and hypersplenism and their causative factors are not clear
Cytopenias, Cirrhotic, Causative, Clear
10. Cytopenias: Obtain complete blood counts (CBC) and platelet counts at weekly intervals during therapy and CD4 counts after therapy until recovery to ≥200 cells/µL
Cytopenias, Complete, Counts, Cbc, Cells
11. KEYWORDS: autoimmune Cytopenias, WAIHA, CAD, ITP, AIN INTRODUCTION Failure to maintain self-tolerance is the dominant pathophys-iologic mechanism binding the autoimmune Cytopenias, a group of disorders characterized by the immune mediated destruction of …
Cytopenias, Cad, Characterized
12. Treatment with the thrombopoietin receptor agonist eltrombopag significantly improved Cytopenias and was well-tolerated in patients with low to intermediate-2 risk myelodysplastic syndromes.
13. Patients with unexplained Cytopenias may never receive a definitive diagnosis, or may eventually be classified as having myelodysplastic syndromes (MDS, a myeloproliferative neoplasm [MPN] or, if their Cytopenias persist, as having idiopathic cytopenia of undetermined significance [ICUS]).
Cytopenias, Classified, Cytopenia
14. Cytopenias with associated "dysplasia" can be the result of medications (especially chemotherapeutic agents)
Cytopenias, Can, Chemotherapeutic
15. Aplastic anemia also presents with Cytopenias and can raise concern for a hypoplastic MDS, but acquired aplastic anemia typically lacks significant morphologic dysplasia and has a normal karyotype.
Cytopenias, Can, Concern
16. Autoimmune Cytopenias are observed in 5% to 10% of patients with CLL, and may precede, occur at time of diagnosis or develop as a complication of therapy
Cytopenias, Cll, Complication
17. Peripheral blood Cytopenias are common in SLE and their management can be challenging
Cytopenias, Common, Can, Challenging
18. Cytopenias after day 28 in allogeneic hematopoietic cell transplantation: impact of recipient/donor factors, transplant conditions and myelotoxic drugs
Cytopenias, Cell, Conditions
19. Hematologists learn early in training how to evaluate patients with Cytopenias, and this remains a core task of hematology clinical practice
Cytopenias, Core, Clinical
20. But when common cytopenia-inducing causes (eg, vitamin or essential mineral deficiency, infection, immune dysregulation, drug effect, bleeding, organ dysfunction, neoplasia) have been systematically excluded, yet Cytopenias persist, clinicians may be
Common, Cytopenia, Causes, Cytopenias, Clinicians
21. Cytopenias may herald or concur with the onset of various systemic rheumatic diseases
22. Autoimmune Cytopenias may be associated with infections, systemic autoimmune diseases, neoplasias, drug toxicity, and other factors
23. The autoimmune Cytopenias are a group of disorders resulting primarily from autoantibody-mediated destruction of blood cells, with variable clinical sequelae depending on the severity and lineage affected
Cytopenias, Cells, Clinical
24. Cytopenias are the most common HIV-associated hematological abnormality
25. Cytopenias have been associated with several factors including sex, race/ethnicity, geographical location and comorbidities such as tuberculosis, hepatitis B infection, fever and oral candidiasis
Cytopenias, Comorbidities, Candidiasis
26. Cytopenias become more prevalent as HIV progresses and are often fatal
27. •Cytopenias: Obtain complete blood counts (CBC) and platelet counts at weekly intervals during therapy and CD4 counts after therapy until recovery to ≥200 cells/µL
Cytopenias, Complete, Counts, Cbc, Cells
28. Chemotherapy-induced myelosuppression (along with other Cytopenias) Hematopoietic cell mutation involving GATA2
Chemotherapy, Cytopenias, Cell
29. Cytopenias are a common feature, but up to 30% of patients can present with cytosis
Cytopenias, Common, Can, Cytosis
30. When Cytopenias remain unexplained despite an appropriate evaluation, they may be described as one of the following : Idiopathic cytopenia of undetermined significance (ICUS) Clonal cytopenia of undetermined significance (CCUS) This topic will discuss the diagnosis and management of unexplained Cytopenias in adults.
Cytopenias, Cytopenia, Clonal, Ccus
31. This article summarizes immune Cytopenias seen in patients with SLE, and it also discusses management of these Cytopenias
32. AB - There are various immune Cytopenias associated with systemic lupus erythematosus (SLE)
33. Bone marrow involvement causes suppression of normal hematopoiesis and consequent peripheral Cytopenias, in our study there was a statistically significant difference in frequency of leucopenia and thrombocytopenia in cases with and without marrow infiltration (table 1) pancytopenia was found in 7 cases (16.6%) with marrow infiltrates in
Causes, Consequent, Cytopenias, Cases
34. Cytopenias are a common end result of this immune dysregulation, and neurologic manifestations can be seen in approximately one-third of those affected with this disorder
Cytopenias, Common, Can
35. 8 – 10 To diagnose diseases such as HLH, the patient must meet at least 5 of the following laboratory and/or clinical criteria: fever, Cytopenias (hemoglobin <9 g/dL
Clinical, Criteria, Cytopenias
Cytopenia is a reduction in the number of mature blood cells. It is common in cancer patients being treated with radiation and/or chemotherapy. Anemia - a reduction of the red blood cells in the body. Leukopenia - a deficiency of white blood cells, or leukocytes Neutropenia - a type of leukopenia, with a specific deficiency in neutrophils
There are also two general types of cytopenia: autoimmune and refractory. Autoimmune cytopenia - caused by an autoimmune disease when your body produces antibodies to destroy the healthy blood cells.
Cytopenia is a reduction in the number of mature blood cells. It is common in cancer patients being treated with radiation and/or chemotherapy. Anemia - a reduction of the red blood cells in the body. Leukopenia - a deficiency of white blood cells, or leukocytes
Cytopenia is a reduction in the number of mature blood cells. It is common in cancer patients being treated with radiation and/or chemotherapy.