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1. Abiraterone is used together with steroid medication (prednisone or methylprednisolone) to treat prostate cancer that has spread to other parts of the body. Abiraterone is used in men whose prostate cancer cannot be treated with surgery or other medicines

Abirate, Abiraterone

2. Abiraterone may also be used for purposes not listed in this medication guide.

Abiraterone, Also

3. Abiraterone acetate is designed to treat these tumors by inhibiting the production of androgen in the testes, adrenal glands, and prostate cancer tumors themselves. The clinical trial included 1,195 patients from 13 countries whose metastatic prostate cancer had previously been treated with one of two chemotherapy regimens that included docetaxel.

Abiraterone, Acetate, Androgen, Adrenal, And

4. ZYTIGA ® (Abiraterone acetate) is a prescription medicine that is used along with prednisone. ZYTIGA ® is used to treat men with prostate cancer that has spread to other parts of the body

Abiraterone, Acetate, Along

5. Abiraterone is a hormone therapy drug. It is a treatment for prostate cancer

Abiraterone

6. You might have Abiraterone: if other hormone treatments are no longer working, and you have no or mild symptoms but you don't need chemotherapy

Abiraterone, Are, And

7. Abiraterone acetate is the generic name for the trade name drug Zytiga®

Abiraterone, Acetate

8. Zytiga contains the drug Abiraterone acetate

Abiraterone, Acetate

9. Abiraterone acetate, a prodrug of Abiraterone, which is a selective irreversible inhibitor of the key enzyme cytochrome P17A1 that is required in androgen biosynthesis, has been approved in combination with prednisone for the treatment of mCRPC.

Abiraterone, Acetate, Androgen, Approved

10. Oral: Administer Abiraterone (Zytiga) orally on an empty stomach, at least 1 hour before and 2 hours after food

Administer, Abiraterone, An, At, And, After

11. No food should be consumed for at least 2 hours before or for at least 1 hour after the Abiraterone (Zytiga) dose

At, After, Abiraterone

12. Abiraterone micronized (Yonsa) may be administered without regard to food

Abiraterone, Administered

13. Abiraterone acetate (Abiraterone or Zytiga ®) is a hormonal therapy drug used to treat advanced prostate cancer

Abiraterone, Acetate, Advanced

14. These help reduce some of the side effects of Abiraterone

Abiraterone

15. Abiraterone is usually given with or after other types of hormonal therapy drugs, if …

Abiraterone, After

16. Effects of Abiraterone on Drug-Metabolizing Enzymes - ZYTIGA ® is an inhibitor of the hepatic drug-metabolizing enzymes CYP2D6 and CYP2C8

Abiraterone, An, And

17. Abiraterone is in a class of medications called androgen biosynthesis inhibitors

Abiraterone, Androgen

18. How should this medicine be used? Abiraterone comes as a tablet to take by mouth on an empty stomach with water, 1 hour before or 2 hours after eating any food.

Abiraterone, As, An, After, Any

19. Effects of Abiraterone on Drug-Metabolizing Enzymes - ZYTIGA ® is an inhibitor of the hepatic drug-metabolizing enzymes CYP2D6 and CYP2C8

Abiraterone, An, And

20. Prior treatment with enzalutamide, Abiraterone acetate, orteronel, galeterone, ketoconazole, aminoglutethimide, estrogens, megestrol acetate, and progestational agents (including cyproterone acetate) for prostate cancer; Prior treatment with radiopharmaceutical agents (e.g., strontium-89) or immunotherapy (e.g., sipuleucel-T) for prostate cancer

Abiraterone, Acetate, Aminoglutethimide, And, Agents

21. Abiraterone is a hormone treatment - it belongs to a group of medicines known as anti-androgens

Abiraterone, As, Anti, Androgens

22. Generic name: Abiraterone acetate

Abiraterone, Acetate

23. Zytiga® is the trade name for the generic drug Abiraterone acetate

Abiraterone, Acetate

24. In some cases, health care professionals may use the generic name Abiraterone acetate when referring to the trade name Zytiga®

Abiraterone, Acetate

25. Abiraterone is a treatment for advanced prostate cancer

Abiraterone, Advanced

26. An Efficacy and Safety Study of Apalutamide (JNJ-56021927) in Combination With Abiraterone Acetate and Prednisone Versus Abiraterone Acetate and Prednisone in Participants With Chemotherapy-naive Metastatic Castration-resistant Prostate Cancer (mCRPC) - Full Text View.

An, And, Apalutamide, Abiraterone, Acetate

27. Abiraterone acetate, a prodrug of the CYP17A1 inhibitor Abiraterone that blocks androgen biosynthesis, is approved for treatment of patients with metastatic castration-resistant prostate cancer (mCRPC) in combination with prednisone or prednisolone 5 mg twice daily

Abiraterone, Acetate, Androgen, Approved

28. Abiraterone is a steroidal compound with antiandrogen activity

Abiraterone, Antiandrogen, Activity

29. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex; CYP17A1), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis.

Abiraterone, Activity

30. Abiraterone is an orally active inhibitor of the steroidal enzyme CYP17A1 (17 alpha-hydroxylase/C17,20 lyase)

Abiraterone, An, Active, Alpha

31. Abiraterone is another hormonal therapy that blocks testosterone production by inhibiting the CYP17 enzyme and is commonly used when resistance to an LHRH therapy develops, which is referred to as castrate-resistant prostate cancer (CRPC).

Abiraterone, Another, And, An, As

32. Patients should also be informed that it is not known whether Abiraterone or its metabolites are present in semen

Also, Abiraterone, Are

33. Abiraterone blocks the effect of the male hormone called testosterone.This medicine is used for certain types of prostate cancer

Abiraterone

34. The lowest GoodRx price for the most common version of Abiraterone is around $259.99, 95% off the average retail price of $6,459.88.

Abiraterone, Around, Average

35. Abiraterone Acetate is an orally active acetate ester form of the steroidal compound Abiraterone with antiandrogen activity

Abiraterone, Acetate, An, Active, Antiandrogen, Activity

36. Abiraterone inhibits the enzymatic activity of steroid 17alpha-monooxygenase (17alpha-hydrolase/C17,20 lyase complex), a member of the cytochrome p450 family that catalyzes the 17alpha-hydroxylation of steroid intermediates involved in testosterone synthesis.

Abiraterone, Activity

37. Abiraterone can also harm an unborn baby if the father is taking this medicine at the time of conception or during pregnancy

Abiraterone, Also, An, At

38. Abiraterone blocks the effect of the male hormone called testosterone.This medicine is used for certain types of prostate cancer

Abiraterone

39. The lowest GoodRx price for the most common version of Abiraterone is around $259.99, 95% off the average retail price of $6,185.16.

Abiraterone, Around, Average

40. Abiraterone ACETATE Savings, Coupons and Information

Abiraterone, Acetate, And

41. Abiraterone (a bir A ter one) blocks the effect of the male hormone called testosterone

Abiraterone

42. Abiraterone was approved by the FDA in 2011 based on a randomized clinical trial that compared Abiraterone plus prednisone to prednisone alone and demonstrated an improvement in median overall survival from 10.7 to 14.8 months

Abiraterone, Approved, Alone, And, An

43. Zytiga (Abiraterone), which was studied in men with metastatic disease that had become resistant to Lupron proved this thesis—volunteers with metastatic, Lupron-resistant prostate cancer who received Abiraterone were shown to live 33% longer than men who received a placebo.

Abiraterone

44. Abiraterone is used in combination with prednisone to treat a certain type of prostate cancer that has spread to other parts of the body

Abiraterone

45. Abiraterone is in a class of medications called androgen biosynthesis inhibitors

Abiraterone, Androgen

46. Abiraterone reduced fertility in both male and female rats, although this was completely reversible 4-16 weeks after Abiraterone was stopped

Abiraterone, And, Although, After

47. Background: Abiraterone acetate, a drug that blocks endogenous androgen synthesis, plus prednisone is indicated for metastatic castration-resistant prostate cancer

Abiraterone, Acetate, Androgen

48. We evaluated the clinical benefit of Abiraterone acetate plus prednisone with androgen-deprivation therapy in patients with newly diagnosed, metastatic, castration-sensitive prostate cancer.

Abiraterone, Acetate, Androgen

49. Abiraterone acetate is administered orally, after which it is hydrolyzed to its active metabolite, Abiraterone

Abiraterone, Acetate, Administered, After, Active

50. Abiraterone is greater than 99% bound to albumin and alpha-1 acid glycoprotein

Abiraterone, Albumin, And, Alpha, Acid

51. The addition of Abiraterone and prednisolone to standard androgen-deprivation therapy as the first treatment for patients with locally advanced …

Addition, Abiraterone, And, Androgen, As, Advanced

52. アビラテロン(Abiraterone)はプレドニゾンと組み合わせて転移のある去勢抵抗性前立腺癌(抗アンドロゲン薬による治療に反応しない癌)の治療に用いられる薬である。 アビラテロン酢酸エステルというプロドラッグの状態で処方される(商品名:ザイティガ(Zytiga))。

Abiraterone

53. Abiraterone (250mg) without Prescription

Abiraterone

54. ZYTIGA (Abiraterone acetate) 250 mg tablets are white to off-white, oval-shaped tablets debossed with AA250 on one side

Abiraterone, Acetate, Are

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ABIRATERONE

Frequently Asked Questions

What is abiraterone acetate used for?

Abiraterone acetate is indicated for use in combination with prednisone for the treatment of men with metastatic castration-resistant prostate cancer who have already received prior chemotherapy containing docetaxel.

Why is abiraterone given with prednisone?

Abiraterone works by reducing androgen production in the body. Androgens are male hormones that can promote tumor growth in the prostate gland. Abiraterone is used together with steroid medication (prednisone or methylprednisolone) to treat prostate cancer that has spread to other parts of the body.

How is abiraterone used to treat prostate cancer?

The addition of abiraterone and prednisolone to standard androgen-deprivation therapy as the first treatment for patients with locally advanced or metastatic prostate cancer improved overall and fa...

Are there any side effects of taking abiraterone?

Other side effects include: hypertension. See below for a comprehensive list of adverse effects. Along with its needed effects, abiraterone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

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